Phospho-histone h2ax ser139
WebThis unit describes immunocytochemical detection of histone H2AX phosphorylated on Ser-139 (γH2AX) to reveal DNA damage, particularly when the damage involves the presence of DNA double-strand breaks (DSBs). These breaks often result from DNA damage induced by ionizing radiation or by treatment with anticancer drugs such as DNA topoisomerase ... WebThe AlphaLISA SureFire Ultra Phospho-Histone H2A.X (Ser139) assay kit is an immunoassay for quantitative detection of phosphorylated Histone H2A.X in cellular …
Phospho-histone h2ax ser139
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WebArtikelname: Phospho-Histone H2A.X (Ser139) Colorimetric Cell-Based ELISA Kit: Artikelnummer: ASB-OKAG01963-2X96W: Hersteller Artikelnummer: OKAG01963-2X96W WebHistone H2AX phosphorylation: a marker for DNA damage. The DNA damage response can be initiated in response to a variety of stress signals that are encountered during …
WebH2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting, immunofluorescence and flow cytometry. … WebHistone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle. In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX.
WebMouse Anti Phospho Histone H2ax Ser139 Fitc Conjugated Antibody, supplied by Upstate Biotechnology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more WebHistone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle. In eukaryotes, DNA double strand …
WebIn eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX. The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs.
WebEarn 25% With Your Citation. Submit Now. Meet Dr. Beaker at ABclonal. Learn More. 03/232024. University of South Florida and Moffitt Cancer Center. 03/242024. Virtual … inspect tooltip chromeWebAnti-phospho-Histone H2A.X (Ser139) Antibody, clone JBW301 is a highly specific mouse monoclonal antibody, that targets Histone H2A.X & has been tested in western blotting, … inspect tool windows 10jess oag-cooperWebJan 13, 2011 · H2AX is phosphorylated at Ser139 by various kinases, including the ataxia telangiectasia-mutated (ATM) protein ( 5–8 ), the AT and Rad3-related protein (ATR; ref. 9 ), and DNA-dependent protein kinase (DNA-PK; ref. 10 ), all of which were reported to be involved in the responses of mammalian cells to DNA double-strand breaks (DSB). jess n nics gray maineWebHistone H2AX is a variant of the nucleosome core histone H2A and is phosphorylated at Ser139 in response to DNA damage. Histone H2AX phosphorylation is considered a specific reporter of double-strand DNA breaks. The protein is also referred to as γH2AX when phosphorylated at Ser139. jess n jim\u0027s steakhouse martin city moWebThis Histone H2AX phospho Ser139 antibody was raised against a peptide including phospho-serine 139 of histone H2AX. Buffer 10 mM sodium phosphate pH 7.5, 150 mM … jess oathoutWebPhospho-H2A.X (Ser139) Antibody detects endogenous levels of H2A.X only when phosphorylated at Ser139. Species Reactivity: Human, Mouse, Rat, … jess northwood reshade