Eif4a3 location
WebAug 4, 2024 · Firstly, we saw that the blocking of eIF4A3 activated the protein p53, a protein that has an important role to play in fighting cancer cells." Dimitris Kanellis, postdoctoral fellow at the ... WebThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
Eif4a3 location
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WebAug 11, 2024 · EIF4A3, a member of the DEAD-box protein family, is a nuclear matrix protein and a core component of the exon junction complex (EJC). Under physiological … WebMar 21, 2024 · EIF4A3 (Eukaryotic Translation Initiation Factor 4A3) is a Protein Coding gene. Diseases associated with EIF4A3 include Robin Sequence With Cleft Mandible …
WebAug 2, 2024 · Eukaryotic initiation factor 4A3 (EIF4A3) is a member of the DEAD-box RNA helicase family and regarded as one of the special components of the exon junction complex (EJC). EIF4A3 is involved in various RNA metabolic processes such as nonsense-mediated RNA decay (NMD) and RNA splicing ( 20, 21 ). WebAug 11, 2024 · EIF4A3, a member of the DEAD-box protein family, is a nuclear matrix protein and a core component of the exon junction complex (EJC). Under physiological conditions, EIF4A3 participates in post-transcriptional gene regulation by promoting EJC control of precursor mRNA splicing, thus influencing nonsense-mediated mRNA decay.
WebNov 19, 2024 · The dysregulation of mRNA translation is common in malignancies and may lead to tumorigenesis and progression. Eukaryotic initiation factor 4A (eIF4A) proteins are essential for translation, exhibit bidirectional RNA helicase function, and act as RNA-dependent ATPases. In this review, we explored the predicted structures of the three …
WebSingle cell type specificityi. The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. …
WebDec 13, 2024 · EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling. Meng X, Li W, Meng Z, Li YMeng X, et al. BMC Cancer, 2024 Nov 28. PMID 36443711; Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation … in for it tory lyricsWebChr Location 17q25.3; chr17:80135214-80147183 (-) GRCh38.p7. Alliance of Genome Resources. Eif4a3 ... J:242590 Miller EE, et al., EIF4A3 deficient human iPSCs and … inforivaWebNov 23, 2024 · Our findings indicate that eIF4A3-induced circMMP9 is an important underlying mechanism in GBM cell proliferation, invasion and metastasis through modulation of the miR-124 signaling pathway, which could provide pivotal potential therapeutic targets for the treatment of GBM. ... In addition, we explored the location of circMMP9 in U87 … inforiver income statementWebOct 2, 2014 · One attractive hypothesis is that alternative splicing of 5' UTR sequences facilitates translation of spliced mRNAs through recruitment of eIF4A3. In support of this, evidence suggests that the role of eIF4A3 in translation includes the ATP-dependent rearrangement of protein-protein or protein-mRNA complexes since this nuclear isoform … infor kings hillWebMar 31, 2016 · View Full Report Card. Fawn Creek Township is located in Kansas with a population of 1,618. Fawn Creek Township is in Montgomery County. Living in Fawn … inforkWebProteini. Full gene name according to HGNC. Eukaryotic translation initiation factor 4A3. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. EIF4A3 (DDX48, EIF4AIII, Fal1, KIAA0111) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. infor item masterWebDownload scientific diagram hsa_circ_0030042 inhibits excessive autophagy through obstructing the recruitment of eIF4A3 to beclin1 and FOXO1 mRNA. A & B. Stable hsa_circ_0030042 overexpression ... infor journal